Unexplained infertility refers to the absence of a clear cause for infertility despite thorough evaluations. In such cases, artificial reproductive techniques, such as intrauterine insemination (IUI) or in vitro fertilization (IVF) , can be employed to overcome the barriers and increase the chances of pregnancy by facilitating fertilization and implantation. These techniques offer hope and options for couples facing unexplained infertility.

Intrauterine insemination (IUI) is an assisted reproductive technique where prepared sperm is directly placed into the woman’s uterus, increasing the chances of fertilization by bringing the sperm closer to the fallopian tubes. IUI is often recommended for couples with mild male factor infertility, unexplained infertility, or when timing of ovulation needs assistance, offering a less invasive and more cost-effective option compared to other assisted reproductive technologies.

In-vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) is an assisted reproductive technique where a single sperm is directly injected into an egg, increasing the chances of fertilization in cases of male infertility or when previous IVF attempts have been unsuccessful. ICSI is a highly effective method that allows couples to overcome various fertility challenges and can be combined with other advanced techniques like preimplantation genetic testing for further customization and success in achieving pregnancy